CD2 anticorps

N° du produit ABIN6251870

Cet anticorps anti-CD2 est un anticorps Souris Monoclonal détectant CD2 dans FACS, IF, WB et Func. Adapté pour Humain et Cat.

Aperçu rapide pour CD2 anticorps (ABIN6251870)

Antigène: CD2

Reactivité: Humain, Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)

Clone: HuLy-m1

Détail du produit anti-CD2 anticorps

Purification: Protein G affinity chromatography

Immunogène: Human thymocytes were used as the immunogen for the CD2 antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Functional Activity (Order SAF formulation)

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Western blot: 1-2 μg/mL

Optimal dilution of the CD2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur CD2

Antigène: CD2

Autre désignation: CD2

Sujet: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

ID gène: 914

UniProt: P06729